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Pan J, Copland I, Post M, Yeger H, Cutz E

Preclinical investigations indicate that the peptide may attenuate behavioral and functional disturbances in rodent models of neurodegeneration induced by neurotoxic agents such as MPTP and reserpine

Zhu CG, Liu YX, Wang H et al (2017) Active form of vitamin D ameliorates non-alcoholic fatty liver disease by alleviating oxidative stress in a high-fat diet rat model

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In a Complete Response Letter, the regulator stated that Aldeyras New Drug Application did not demonstrate efficacy in treating ocular symptoms associated with dry eyes and informed the company that at least one additional adequate and well-controlled study would be required to demonstrate efficacy

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