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A meta-analysis of clinical trials, including data from Novo Nordisk itself, found higher incidence of optic ischemic neuropathy in GLP-1 groups compared to placebo

Russell-Jones D, Vaag A, Schmitz O, et al

Initial fears of pancreatitis and thyroid cancer have not been substantiated by large-scale analyses or rigorous FDA/EMA evaluations [65, 68, 69] (e.g., human thyroid tissue lacks GLP-1 receptor expression)

Nutritional modulation of age-related macular degeneration

Once absorbed, intracellular esterases remove the acetyl group to release free glutathione

Metformin has been associated with bile acid malabsorption, which can cause severe diarrhea