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As GLP-1 agonists, their active ingredient is semaglutide, which mimics a naturally occurring hormone called glucagon-like peptide-1 (GLP-1)

However, the presence of side effects doesn't determine weight loss successmany patients achieve excellent results with minimal nausea from day one

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This confounded efforts to establish whether it had insulin secretory properties (Marks 2020)

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In patients who have major depressive disorder, there is a decrease in the physical size of the hippocampus