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So, for about half a century, theres been healthy skepticism about new-kid-on-the-block obesity drugs promising profound weight loss, only to see one after another fail and flop

It is usually mild to moderate and tends to improve over time as the body adjusts to the medication

While not always separately quantified in clinical trial data, bloatingcharacterized by a sensation of abdominal fullness, distension, or tightnessis recognized as part of the broader spectrum of gastrointestinal side effects associated with GLP-1 receptor agonists

Glial cells to a very great extent define neuropathology, its progression and outcome: as long as glial defence prevails, the pathological process is resolved, whereas the failure of glial defence results in neuronal death and neurological deficits

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Vaishnava S, Yamamoto M, Severson KM et al (2011) The antibacterial lectin RegIII- promotes the spatial segregation of microbiota and host in the intestine