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These pieces of evidence further support a role of P4HA1 in collagen fibril contraction upon dysmetabolic conditions

Sci., 11, e70208, 2025

Efficacy was seen in both patients with proliferative LN alone, as well as those with a concurrent membranous (MLN) component

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In addition, LS mean comparisons were performed using Tukeys t-test

Risk Tier: LOW-MODERATE This rating reflects the compound's bioactive epigenetic and telomerase-related modulation activity in preclinical models and the need for proper handling to prevent accidental exposure during reconstitution