This results in consuming fewer calories, contributing to weight loss over time
Gradual body composition shifts : Rather than rapid weight drops, microdose patients tend to lose one to two pounds per week with less muscle wasting
However, levels of the intestinal hormone peptide YY (PYY) were elevated in the blood, and this effect was suppressed by a TRPA1 channel blocker 23
IMPORTANT NOTICE: This unregistered medicine has not been evaluated by the SAHPRA for its quality, safety or intended use
is also a consultant for Netdoktor and has served as principal investigator in relation to the development of drugs for the treatment of type 2 diabetes and obesity in collaboration with Novo Nordisk and Bayer, with funds paid to the institution where he is employed, with no personal fee and with no relation to the work reported in this article
a) Somatostatin b) Glucagon c) Ghrelin d) Cortisol Answer: b) Glucagon Typical onset of gastric emptying delay is: a) Within minutes b) Within hours c) After weeks d) No effect Answer: b) Within hours Semaglutide injection frequency is: a) Daily b) Weekly c) Monthly d) As-needed Answer: b) Weekly A rare but serious adverse effect to monitor is: a) Hypoglycemia b) Pancreatitis c) Hyperthyroidism d) Nephrolithiasis Answer: b) Pancreatitis It is contraindicated in patients with: a) Type 1 diabetes b) Medullary thyroid carcinoma c) Obesity d) Hypertension Answer: b) Medullary thyroid carcinoma Compared to exenatide, semaglutide yields: a) Less weight loss b) More weight loss c) Higher injection frequency d) Less HbAc reduction Answer: b) More weight loss Half-life of semaglutide is approximately: a) 24 hours b) 3 days c) 7 days d) 15 days Answer: c) 7 days Excretion involves: a) High renal elimination b) Only feces c) Metabolism and minimal excretion d) Biliary excretion Answer: c) Metabolism and minimal excretion An added cardiovascular benefit was shown in: a) SUSTAIN trials b) DPP4 studies c) RAAS inhibitor trials d) REM sleep studies Answer: a) SUSTAIN trials Weight loss percentage ranges from: a) 15% b) 510% c) 1017% d) 2025% Answer: c) 1017% A significant GI side effect is: a) Increased appetite b) Nausea c) Insomnia d) Hypertension Answer: b) Nausea Semaglutide metabolism involves: a) CYP3A4 b) Proteolysis c) Renal enzymes only d) Conjugation Answer: b) Proteolysis An advantage over liraglutide is: a) Lower efficacy b) Higher weight loss c) Daily dosing d) Less frequent injection Answer: d) Less frequent injection FAQs Does semaglutide cause weight loss in non-diabetic patients
