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No differences in the pharmacokinetics of TRESIBA were identified between healthy subjects and subjects with hepatic impairment [see Use in Specific Populations (8.7)]

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The coenzymes of this vitamin are highly unstable in light.[6] Cyanocobalamin is available in several dosage forms including the tablet, nasal spray, and injection

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After reconstitution, they must be kept refrigerated and used within the recommended timeframe to ensure stability