Tirzepatide has helped me learn better eating habits (Protein, Fiber, Healthy Fats), that has lowered blood pressure & improved overall health
PlexusDx patients can access the Precision Peptide Genetic Test to identify genetic predispositions in the FTO and MC4R pathwaysvariants that influence how your body metabolizes lipids and controls appetite
At each meal, aim for roughly: A quarter of your plate as protein (about a palm-sized portion): chicken, fish, eggs, Greek yoghurt, tofu, or legumes
Resistance to leptin, the satiety hormone, is considered a prominent driver of obesity
HRT and GLP-1: What Women Need to Know About Combining These Therapies At a glance Primary GLP-1 agents used with HRT / semaglutide 2.4 mg (Wegovy) and tirzepatide 15 mg (Zepbound) Mean weight loss with semaglutide 2.4 mg / 14.9% at 68 weeks in STEP-1 (N=1,961) Estrogen effect on visceral fat / transdermal 17-beta-estradiol reduces visceral adiposity by ~6-7% vs placebo per RCT data Oral estrogen risk with GLP-1 / slowed gastric emptying may reduce absorption
Related Reading: For a comprehensive overview of IGF-1 LR3 mechanisms and muscle biology, see our IGF-1 LR3 UK Complete Research Guide 2026
