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Late stage PD is characterised by increasing disability from drug-refractory motor and non-motor symptoms including gait and balance problems, impaired speech and swallowing, autonomic dysfunction, and cognitive decline for all of which there is currently little prospect of highly efficacious drug therapies

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Conclusions Warfarin is a powerful anticoagulant that interacts with a broad spectrum of nutrients most of which are not included in daily clinical practice guidelines perhaps its time they are