Leaner individuals may see slower but steady improvements in particularly resistant areas
heartburn, acid regurgitation, belching, bloating, abdominal distension, chest pain, postprandial fullness, early satiety, and flatulence
21-23 In the case of pill-induced oesophagitis, treatment involves withdrawal of the offending medication where possible and the use of proton pump inhibitors
Another 23% said they remained at a lower weight after stopping the drug
If you take oral contraceptives, the efficacy may be reduced
Diabetes Care 24:489494 Green BD, Irwin N, Duffy NA, Gault VA, OHarte FP, Flatt PR (2006) Inhibition of dipeptidyl peptidase-IV activity by metformin enhances the antidiabetic effects of glucagon-like peptide-1