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These initial findings collectively help establish a pre-clinical framework for the future studies involving ferroptosis as a potential therapeutic target in therapy-resistant advanced thyroid cancers

The involvement of the NLRP3 inflammasome pathway has also been implicated, with pharmacological inhibition of TLR4/NF-B/NLRP3 signaling attenuating neuroinflammation and improving tinnitus behavior in noise-exposed mice (Luo et al., 2024)

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