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Adjust therapy as needed

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Do not inject through clothing

Cell transfection MPC5 cells were transfected with SIRT5-targeting short hairpin (sh) RNA (shSIRT5), shRNA negative control (shNC), pcDNA3.1 empty vector, or transferrin receptor 1 (TFR1) overexpression plasmid (pcDNA3.1-TFR1) using Lipofectamine 3000 (#L3000001

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We are grateful to the volunteers and diabetic patients for their participation in the study