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The trial included patients with mild to moderate kidney disease, with estimated glomerular filtration rates ranging from 25 to 75 mL/min/1.73 m 2 and elevated UACR

As an example, the combination of GLP1RA liraglutide with metformin in infertile obese PCOS patients increased the pregnancy rate after IVF treatment compared to metformin treatment alone although weight loss was similar in these groups, 52 supporting the hypothesis of endometrium as an effective target for GLP1RA therapy

Skepticism also reflects legitimate concerns about cost and access in traditional medical settings

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