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These research-stage amylin-based candidates differ in receptor focus, molecular design, clinical evidence, side-effect profile, and development strategy

Although small amounts of nitrite formed as an end product of the NOS-dependent pathway contribute to the nitratenitriteNO pathway, the most abundant source of nitrite-derived NO is the reduction of nitrates consumed in the diet

The essential role of IGFs in cell growth is shown by the report that fibroblasts from IGF-1 receptor knockout mice grew very slowly in culture unless they were transfected with a plasmid expressing the IGF-1 receptor

A similar strong de-regulation of DNA replication-related genes was seen by the same group when treating bladder cancer cell line T24 with medium doses (0.25 mM) of VitC [171]

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Single-agent liposomal all-trans retinoic acid can cure some patients with untreated acute promyelocytic leukemia: an update of The University of Texas M