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Description

Heat and cold treatments have fallen out of favor in recent years

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Chenodeoxycholic acid (CDCA) and cholic acid (CA) are primary BAs produced in humans, and their ratio is determined by the enzyme sterol 12-hydroxylase (CYP8B1)

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Moreover, ferroptosis is a critical pathophysiological event in FA-induced AKI, characterized by the imbalance of redox homeostasis and lethal lipid-based reactive oxygen species (ROS) generation (Martin-Sanchez et al., 2017)

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