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In reactive astrocytes, MAO-B activity is notably elevated, leading to increased production of H 2 O 2 , while NADPH oxidase 2 is frequently upregulated, further amplifying ROS generation [359, 363]

Mitochondrial Dysfunction and Mitophagy in Parkinsons Disease: From Mechanism to Therapy

The findings showed that AST considerably improved short-term memory, lowered brain acetylcholinesterase activity, and had neuroprotection and anti-amyloidogenic effects

10.1126/science.1096284 Science 129 VanderkuurJ

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This important protein plays a central role in how hormones like testosterone and estrogen are transported and accessed in the body