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Common side effects include nausea, vomiting, diarrhea and constipation

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In the UK, GLP-1 receptor agonists are prescription-only medicines , regulated by the Medicines and Healthcare products Regulatory Agency (MHRA)

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Figure 7 The treatment of primary CLL lymphocytes with CB-839 alone increased mitochondrial superoxide production in both unstimulated (n = 15) and stimulated (n = 19) conditions (P = 0.006 and P = 0.02, respectively