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Skin tightening surgeries such as Renuvion (J-Plasma) also do better with general anesthesia

This gap between preclinical promise and human clinical validation is the defining characteristic of the current pipeline

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Moreover, although statistically insignificant, extrathyroidal tumor extension, which is known to be associated with poor prognosis in PTC, showed a non-significant positive correlation with GLP-1R expression in PTC in our study

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However, these effects are typically small and inconsistent across studies, and the mechanisms remain poorly understood