Research on the MOTS-c analog CB4211 used 25 mg per day (a much higher dose), but native MOTS-c protocols trend lower
In both mouse and human cells, the researchers showed that the plant-derived drug caused a variety of cell types, including oral-tissue cells and osteoblasts, or bone-building cells, to grow and differentiate, or divide to form a variety of different cell types
Mild side-effects like heartburn and indigestion are possible, and I usually keep the dose to around 2 grams a day
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N.SaadM
Given their distinct mechanisms, there could be synergistic research opportunities, though such studies require rigorous control