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From a weight loss efficacy perspective, the bar has been set by tirzepatide

There is a strong argument that it does

Additionally, consistent with previous meta-analyses by Popovic et al

Body Weight Reduction in Women Treated with Tirzepatide by Reproductive Stage: A Post Hoc Analysis from the SURMOUNT Program. Obesity , vol

"When there is a severe insult to the liver, the liver cells can die, and we can see this in a blood test when we look at the inflammation in the liver