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The human glutathione transferase P1-1 specific inhibitor TER 117 designed for overcoming cytostatic-drug resistance is also a strong inhibitor of glyoxalase I

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Research from the STEP trials (semaglutide) and SURMOUNT trials (tirzepatide) demonstrates that GLP-1 agonists produce 1522% body weight loss in people with obesity, significantly outperforming older weight loss medications