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In fact, several molecules known as BDNF mimetics have already been developed, including BDNF loop dipeptide mimetics such as GTS-201, GSB-106, and GSB-214, as well as the natural product 7,8-dihydroxyflavone 33,34,35,36,37

Aqueous extract of Scrophularia ningpoensis improves insulin sensitivity through AMPK-mediated inhibition of the NLRP3 inflammasome