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Case series, such as that described by Lotz-Havla et al

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Abulfadle et al., 2015) have declared that excessive and high doses of green tea have the potential to alter the thyroid gland physiology and architecture, that is, enlargement of thyroid gland as well as hypertrophy and/or hyperplasia of the thyroid follicles and inhibition of the activity of thyroid peroxidase and 50-deiodinase I with elevated thyroidal sodium-potassium- ATPase activity along with significant decrease in serum T3 and T4, and a parallel increase in serum thyroid stimulating hormone (TSH)