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Exenatide Once Weekly Versus Placebo in Parkinsons Disease: A Randomised, Double-Blind, Placebo-Controlled Trial
They aim to mimic injectable GLP-1 receptor agonists by activating appetite and metabolism pathways
Nephron 144 , 595606 (2020)
Mild appetite reduction, possible GI side effects Month 2 (still 2mg): Additional 3-5 lbs
By week 12, the mean blood pressure decreased from baseline in the LY group compared to the placebo group
In the literature, Retatrutide has been investigated in relation to: body-weight regulation and appetite signalling glucose metabolism and glycaemic markers energy expenditure and substrate utilisation multi-pathway incretin research next-generation obesity and metabolic-disease models For researchers comparing newer metabolic peptides, Retatrutide is often discussed alongside Semaglutide and Tirzepatide because it extends beyond GLP-1/GIP into triple-pathway metabolic modulation
