Most of what we know comes from preclinical and experimental research, rather than human trials
As a result, it may be more effective in providing antioxidant protection and increasing glutathione levels
Through co-immunoprecipitation (CO-IP) experiments, we discovered that FOXO4-DRI prevents the binding of FOXO4 to P53, facilitating the phosphorylated P53 nuclear exclusion, which subsequently trigger BAX and cleaved caspase-3, leading to the apoptosis of senescent cells
For needle-free coverage beyond the face and scalp, our GHK-Cu + AHK-Cu body wash extends the same peptide class to the rest of the body in a daily shower step
Glycyl-l-histidyl-l-lysine prevents copper- and zinc-induced protein aggregation and central nervous system cell death in vitro
However, like most other medical treatments their efficacy would depend on the patient and extent of these hyperpigmentations or scarification processes