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Just an overall reduction in volume and density

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This makes it hard for nerves to repair themselves

After 30, our bodies start to break down due to increasingly fragile cells, less efficient mitochondria, and an increased need to support immunity and metabolism

The research record is based on animal models and mechanistic reasoning

Quick answer: In head-to-head trials, tirzepatide (a dual GLP-1/GIP receptor agonist) produced greater weight loss than semaglutide (a single GLP-1 agonist) 20.2% vs 13.7% over 72 weeks in SURMOUNT-5 though semaglutides single-pathway selectivity keeps it valuable in research