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Important safety warnings: If you experience severe, persistent abdominal pain (which may radiate to your back), stop taking Rybelsus immediately and seek urgent medical attention as this could indicate pancreatitis Be aware of potential gallbladder problems (upper right abdominal pain, fever, yellowing of skin/eyes) Severe vomiting or diarrhoea can cause dehydration and affect kidney function

Furthermore, a retrospective study using TriNetX found that treatment with a GLP1-RA at any point following a LN diagnosis reduced the 5-year rate of progression to ESRD by half14

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At the highest tested dose of 12 mg, 24.2%

Diabetes 68(5):9881001