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This study was supported by the EHA Ukraine Bridge Funding awarded by the European Hematology Association, Ministry of Health of the Czech Republic (DRO - VFN00064165), National Institute for Cancer Research (EXCELES - LX22NPO5102), Ministry of Education, Youth, and Sports of the Czech Republic via Charles University (Cooperatio Program, research area Biology)

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Steuerman R, Shevah O, Laron Z: Congenital IGF1 deficiency tends to confer protection against post-natal development of malignancies

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Furthermore, enhancer factor 2 (EF2) acts as a downstream effector within the TGF-1 pathway and plays an essential role in HSC activation and the progression of fibrosis