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Therefore, patients with the rs2108622 polymorphism are likely to have elevated hepatic levels of VK1, necessitating a higher warfarin dose to elicit the same anticoagulant response (54)

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A 2025 systematic review by Vasireddi and colleagues in Emerging Use of BPC-157 in Orthopaedic Sports Medicine (Sports Health) found that, across mostly preclinical models, BPC-157 may improve tendon and ligament healing though the authors stress that human evidence remains limited and BPC-157 is not FDA-approved