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In a combined fertility and embryo-fetal development study in rats, subcutaneous doses of 0.01, 0.03 and 0.09 mg/kg/day (0.04-, 0.1-, and 0.4-fold the MRHD) were administered to male and female rats

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Residual solvents, water content, microbial expectations, and endotoxin expectations may matter depending on the model

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Acta Pharmacol Sin 36 , 323 (2015)