doi: 10.1016/j.pt.2020.07.001 129 ThakurV.IslamM
F-652 is a human IL-22 recombinant fusion protein composed of human interleukin 22 (IL-22) and human IgG2 Fc fragment, and its mechanism of action is similar to that of natural IL-22
Superoxide anion (O 2 - ), hydroxyl (OH ), alkoxy radicals (RO ), peroxyl radicals (ROO ), nitric oxide radical (NO ), nitrogen dioxide (NO 2 ), and carbonate radical (CO 3 - ) are the few examples of radical ROS whereas non-radical ROS include singlet oxygen ( 1 O 2 ), hydrogen peroxide (H 2 O 2 ), hypochlorous acid (HOCl), and peroxynitrite (ONOO - ) species which can readily trigger free radical reactions in organisms [23, 24]
10.1093/jn/133.11.3927S 274
Turegano is cautious when recommending the ingredient to those with dry and sensitive skin because of the irritation it can cause
Critically, the oxidative breakdown of integrated PUFA-PLs affects membrane integrity whereas isolated olyunsaturated fatty acid hydroperoxides (PUFA-OOH) have no membrane-disrupting properties (Liu et al., 2024)