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The brain has a high demand for continuous nutrient and energy supply, and malnutrition can induce cerebral energy failure [25]

Notably, when JNK and Nrf2 expression is silenced, AS-IVs protective effects on pancreatic oxidative stress in DKA are diminished, though AS-IV still improves glucose and insulin levels in these juvenile mice (Li et al., 2023)

The authors also validated that GSH content and GPX4 activity were significantly decreased when H22 cells were co-incubated with Mn-MOF (Figures 5H, I)

This grain is notable in human and functional nutrition for its high-quality protein, unsaturated lipids, and antioxidant bioactive compounds