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Availability of data and materials Data described in the manuscript will be available upon request and approval by the UK Biobank ( References Oppenheimer GM, Benrubi ID

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There are also emerging geographic and demographic disparities: studies have found lower GLP-1 fill rates among patients with obesity (37% fill rate) versus those with diabetes (4765% fill) ( [30] ), and lower fill rates for Hispanic and Black patients, reflecting both socioeconomic and coverage gaps ( [31] )