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10.1016/j.biopha.2022.114142 196 HuJ.LiH.WangX.ChengH.ZhuG.YangS

2.8 Data analysis 2.8.1 Data analysis of UGT induction The formation of glucuronide metabolites, as determined with LC-MS, was used to calculate the formation rate linked to enzyme activity according to Equation 1

These polyphenolic compounds, particularly chlorogenic acid and caffeic acid found abundantly in coffee, possess multiple hydroxyl groups that act as binding sites for iron molecules [1]

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(PubMed) Shamim AA, Schulze K, Merrill RD, et al