The locus coeruleus contributes to the anorectic, nausea, and autonomic physiological effects of glucagon-like peptide-1
Similarly, once-a-day Saxenda (liraglutide) over 56 weeks led to an average of 8% weight loss, with 63% of participants experiencing clinically significant weight loss
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and Park, et al
AOM tirzepatide prescription rates increased by an average of 0.06 percentage points a month from January 2024 to June 2025 but grew only by 0.03 percentage points between June and July