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Parasitism, commensalism, and mutualism: exploring the many shades of symbioses

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On average, adults were in the trial for 3.5 years (41.8 months)

No, this is generally not an issue

Patients taking bupropion for smoking cessation may also experience changes in mood, psychosis, hallucinations, paranoia, delusions, homicidal ideation, hostility, aggression, anxiety, and panic, as well as suicidal ideation, suicide attempt, and completed suicide, high blood pressure, fast, irregular heartbeats, seizures, acute angle-closure glaucoma, and death