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152 RadakD.KatsikiN.ResanovicI.JovanovicA.Sudar-MilovanovicE.ZafirovicS.et al (2017)

Skipping the lipidation step produces a ~3,400 Da unmodified amylin analog, which is why mass spec matters here more than it does for simple peptides

doi: 10.1016/0002-9343(79)90648-X 76 MoscaPRobertAAlbertoJMeyerMKunduUHergalantSet al

This happens because excess cholesterol solidifies, leading to gallstones

Due to insufficient protein yield from individual healthy bile samples for robust MS analysis, the four normal bile samples were pooled and labeled with the TMT-126 reporter channel in both TMT sets

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