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Since GLP-1 is rapidly degraded by DPP-4 and both peripheral and central GLP-1 reduces food consumption, it has been proposed that there may be a signaling link between peripheral GLP-1R activation and central GLP-1 release from the nucleus of the solitary tract (Trapp and Hisadome, 2011)

Referenced Citation Jastreboff AM, et al

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Specific gene mutations may be inherited, increasing susceptibility to melanoma