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mTORC2 signaling regulates PI3K signaling in early B cells to upregulate IL-7R signaling and Rag gene expression, and pathway disruption results in interrupted B cell development [76]

In this review, we discuss how peptide-based tumor immunotherapy transforms PCa from a cold to a hot state by modulating the TME of PCa and inducing ICD in PCa cells, thereby enhancing the response of PCa to immunotherapy

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