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Decreased Intake issues: A vegan or vegetarian diet with no animal products Poor Absorption Issues Medications that block absorption of B12 Pernicious anemia Auto-immune disorders An Helicobacter pylori (H

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Persistently high levels are more commonly linked to supplements or medical conditions

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Additionally, metformin can also reduce body fat secondary to optimizing insulin, glucose and glycogen, thus decreasing blood sugar levels and increasing demand of fatty acids used for energy