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While these medications can be effective at helping individuals achieve a healthier body weight, many patients are unaware of an important side effect: the unintended loss of lean muscle mass and bone density

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The compound appears at measurable concentrations in human plasma, saliva, and urine, and its levels are known to decline with age a pattern that has driven considerable interest in its study as a research tool

10.1002/mnfr.201800427 23 HolmanJ