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14,15 In addition, results reported by Masarone suggest that liver injury is associated with progressive clinical manifestations of IR, and the histological features of NASH are observed on liver biopsy in 98% of T2DM patients, suggesting that NASH may be one of the early complications of T2DM, as they are both pathophysiologic associated with IR

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"Regulation of insulin-like growth factor I receptor expression by the pure antiestrogen ICI 182780." Clinical cancer research: an official journal of the American Association for Cancer Research 2.12 (1996): 2037-2042