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Nat Med 29(4):898-905, 2023

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The subjects included in the population pharmacokinetic analysis covered a broad range of baseline characteristics: age ranged from 20 to 86 years, body weight ranged from 39.7 to 198.3 kg, duration of diabetes ranged from 0 to 48.9 years, and HbA 1c ranged from 5.9% to 13.1%

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A review of forty-nine observational studies published in the May 2011 issue of the Cochrane Database of Systematic Reviews concluded that higher selenium exposure reduces overall cancer incidence by about 34 percent in men and 10 percent in women, but notes these studies had several limitations, including data quality, bias, and large differences among different studies