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Factors such as alcohol consumption frequency, dosage and frequency of acetaminophen, and individual variations in liver function can also influence the severity of the risks involved

Although these findings may a priori not be applicable for a proper exposure assessment in other countries, it seems plausible to estimate that normal daily intake rates via Western-style diets (not by enriched products) may not exceed 200 mg/d

Asian Pac J Cancer Prev 17:46814688

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Therefore, the development of protective agents capable of achieving local and stable rectal delivery remains a significant clinical need

2016;11(3):e0151653