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In the body, IGF-1Ec/MGF expression rises in muscle and other tissue after mechanical stress or damage, where it acts as an early repair-phase signal that helps start regeneration

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Vahldieck C, Cianflone E, Fels B, Lning S, Depelmann P, Sabatino J, Salerno N, Karsten CM, Torella D, Weil J, Sun D, Goligorsky MS, Kusche-Vihrog K

Efficacy and safety of semaglutide 2.4 mg for weight loss in overweight or obese adults without diabetes: An updated systematic review and meta-analysis including the 2year STEP 5 trial