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Characteristics of the included trials In total, twenty-two randomised trials with 1710 participants proved eligible for inclusion in the present meta-analysis (Reference Ahmed Al-Naggar, Osman and Abdulghani23Reference Wedick, Brennan and Sun44) (Table 1)

Glutamate-induced apoptosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis inducing factor (AIF) and this process is inhibited by equine estrogens

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PMID 30717170

Every batch is third-party tested in USA laboratories to ensure the highest quality, purity and potency

Serious reactions are uncommon when administered under clinical supervision, but any unusual or concerning symptoms should be discussed with a licensed healthcare provider right away