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Frontiers in Endocrinology, 14, 1174545

IFN- regulates xanthine oxidase-mediated iNOS-independent oxidative stress in maneb-and paraquat-treated rat polymorphonuclear leukocytes

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They found in their research that the circulating lipopolysaccharide (LPS) and glucose levels were dramatically elevated in the fecal microbiota transplantation (FMT) rat model, leading to the up-regulated expression of NOD-like receptor protein (NLRP)-3 inflammasome, which contributed to AF, thus promoting the occurrence of AF