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Waiting for 30-year thyroid safety data while allowing obesity-related damage to accumulate seems like poor risk management to me

Both approaches work, as long as storage protocols are followed

In the pancreas, semaglutide enhances glucose-dependent insulin secretion, meaning it only triggers insulin release when blood sugar is elevated

Similarly, GLP-1 binds to GLP-1-receptors (GLP-1r) and causes the same glycemic effect as GIP on the pancreas

The Hair Loss Link Hair loss is a side effect observed in certain retatrutide patients

Regarding FDA approvals , Mounjaro is primarily approved for managing type 2 diabetes , although it has shown significant weight loss in studies