For individuals requiring more intensive glycemic control, recommendations are based on expert opinion and are graded as limited recommendations due to the increased risk of hypoglycemia and insufficient high-quality evidence
The results, which were published in the Lancet on Thursday, are very encouraging for the safety and efficacy of orforglipron in people with type 2 diabetes, says Daniel Drucker, an endocrinologist at the University of Toronto, adding that he is awaiting further clinical trial results of the drug in people with obesity
In the SOUL trial, oral semaglutide was evaluated for its CV effects in individuals aged 50 years with T2D and established ASCVD or CKD
The researchers then carried out a statistical test on this data to assess whether alopecia was reported more often in people taking the GLP-1 RA than would normally occur in the FAERS database as a whole (this is known as a disproportionality analysis)
For many, the results are not just skin-deep but extend to overall energy, detoxification, and long-term vitality
Comment: Several commenters requested that CMS does not finalize the proposed changes to the Diagnostic Tests and Related Services APC series