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Preclinical investigations have showcased the plants capacity to modulate mitochondrial function and apoptosis, as well as mitigate inflammation through the inhibition of inflammatory markers such as cytokines (including IL-6 and TNF-), nitric oxide, and reactive oxygen species

Figure 3 2.3 Molecular pathways regulating CL function 2.3.1 MAPK/ERK signaling The mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) mediates a luteotrophic and luteolytic signaling in the corpus luteum (CL) (66)

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